Threshold stasis 3 manual5/28/2023 In a proportion of women (5–10%), the count will reach levels of 100–150 × 10 9 cells/l by term and this occurs in the absence of any pathological process. The platelet count tends to fall progressively during normal pregnancy, although it usually remains within normal limits. Despite this haemodilution, there is usually no change in mean corpuscular volume (MCV) or mean corpuscular haemoglobin concentration (MCHC). Because the expansion in plasma volume is greater than the increase in red blood cell mass, there is a fall in haemoglobin concentration, haematocrit and red blood cell count. 2 Most of this 50% increase occurs by 34 weeks’ gestation and is proportional to the birthweight of the baby. ![]() Plasma volume increases progressively throughout normal pregnancy.
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